Individuals using weight-loss injections such as Mounjaro and Wegovy are at risk of losing muscle mass equivalent to “10 years of ageing” if they do not engage in strength training, according to recent research. The study highlights that while these drugs facilitate rapid fat loss, they also contribute to significant lean muscle loss, similar to effects observed after bariatric surgery or during cancer treatment.
The loss of muscle and bone mass associated with these medications can increase the risk of frailty and falls, particularly among older adults. This issue has significant financial implications, with the NHS incurring costs of approximately £2.3 billion annually due to falls and related injuries. It is estimated that around 2.5 million people in the UK are currently using weight-loss drugs.
Importance of Strength Training
Dr. Matthew Wade, interim director of research at UKActive, emphasized the necessity of incorporating exercise into weight-loss treatment plans. “The rapid rollout of GLP-1 has shown dramatic results for patients, but in order to avoid weakening the body, there are simple and effective strength exercises, which are essential for sustainable results,” Dr. Wade stated. He advocates for a collaborative effort involving the government, fitness, nutrition, and pharmaceutical sectors to provide comprehensive support for patients undergoing weight-loss treatments.
A report released by Les Mills and UKActive calls for gyms across the UK to develop tailored programs for individuals using weight-loss medications. The injections, known as GLP-1 receptor agonists, function by mimicking a natural hormone that regulates blood sugar, appetite, and digestion, resulting in reduced calorie intake and subsequent weight loss. Both the NHS and the National Institute for Health and Care Excellence (NICE) recommend that these medications be supplemented with dietary changes and physical exercise.
Recommendations for Physical Activity
“Regular strength training is vital to our health at all stages of life, but the research suggests this is especially true for people taking weight-loss medications,” said Bryce Hastings, head of research at Les Mills. The recommendation includes engaging in strength training two to three times a week, alongside accumulating 150 minutes of moderate to vigorous physical activity each week. Such practices not only promote continued fat loss during the maintenance phase of treatment but also mitigate the risk of weight regain once the treatment concludes.
Hastings acknowledged the need for further research to thoroughly explore the relationship between weight-loss medications and strength training. He noted that the recommendations outlined in the report present practical steps to better support the increasing number of individuals utilizing weight-loss medications.
As the popularity of weight-loss injections rises, the emphasis on a balanced approach that includes strength training and physical activity becomes crucial for long-term health and well-being.
